Sickle Cell

SICKLE CELL ANEMIA Introduction Sickle sales booth disease is a elementric term for a group of brokertic form caused by the ?-globin ingredient called reap hook hemoglobin (Hb S) (Kock et al., 2000). The ?-globin broker is located on the short arm of chromosome 11, and it is a ingredient of the globin gene family involved in oxygen channelize (Koch et al., 2000). Sickle cubicleular teleph one disease is the about super C star gene disorder in black Americans, and is also common in persons from Mediterranean countries, Turkey, the Arabian Peninsula, Caribbean, and the Indian subcontinent (Wethers, 2000). It is estimated that more than 50,000 Americans are affected with sickle cubicle disease, making this disease a one of the most prevalent genetic disorders in the united States (Kock et al., 2000). There are several forms of sickle mobile phone disease, and the most common forms are sickle mobile phone anemia, the sickle ß-thalassemia synd romes, and hemoglobinopathies (Wethers, 2000). In sickle cell anemia, also called homozygous sickle cell disease (or SS disease), the individual inherits a sickle (S) gene from separately parent (Wethers, 2000). In the sickle ß-thalassemias, individuals have a sickle (S) gene and gene for ß-thalassemia (Wethers, 2000).

In hemoglobinopathies or doubly heterozygous sickle cell disease, the sickle (S) gene is associated with another atypical hemoglobin, such as C, D, G or O (Wethers, 2000). The cause of sickle cell disease vary greatly from one person to the next. just about affected people rarely are ill opus others are frequently hos pitalized. In contrast to this disease, ther! e is the author in which an individual delight a normal gene (A) in association with the sickle (S) gene. This carrier state is referred to as a sickle cell trait and these individuals: (i) are protect from malaria infection (Aluoch, 1997), (ii) do not express sickle cell disease unless under crotchety circumstances such as marked hypoxia (National Institute of health [NIH], 1996), and (iii) can pass the...If you exigency to get a teeming essay, order it on our website: BestEssayCheap.com

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